Supplementation with the short-chain fatty acid propionic acid (PA) could help reduce excessive inflammatory processes in autoimmune diseases like multiple sclerosis (MS) and improve treatment outcomes.
A new international study, involving roughly 300 subjects with MS, provides further evidence of the hypothesis that short-chain fatty acids (SCFAs) are reduced in autoimmune diseases, such as MS, as a consequence of an altered gut microbiome.
The research team from the Department of Neurology of Ruhr-Universität Bochum (RUB) at St. Josef-Hospital, in Germany, believe this decreased presence of SCFA’s leads to reduced Treg cell function, which might be reversed by supplementation of SCFA’s.
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