MS Fatigue: How To Fight Fatigue With MS Updated on January 04, 2021 Medically reviewed by Alissa Willis, M.D. Article written by Kelly Crumrin Fatigue is a very common symptom of multiple sclerosis (MS) and can be a disabling and frustrating symptom with a huge impact on quality of life. Between 75 percent and 95 percent of people with (430) (838) (515) MS experience fatigue. How Is MS Fatigue Different From Normal Fatigue? Fatigue in MS is different in many ways from the tiredness people may experience as the result of a long day at work or a late night out. Fatigue is also different from sleepiness, although staying in bed may be the only thing that seems to help at times. According to the National Multiple Sclerosis Society, people with MS commonly experience fatigue that persists daily, even after plenty of sleep, and worsens as the day goes on.
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